The cees dekker Diaries

Rotary movement of DNA rotors on nanopores. Best row: Uncooked movie from the Cy5 channel of each and every rotor. Middle row: corresponding one-particle localization outcomes of both of those ends of your DNA rotors. The placement of the current body is marked as orange and blue dots, along with the trajectory of the 10 frames ahead of the current frame is revealed as reliable strains.

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[Laughs] ‘It absolutely was unquestionably an awesome hazard! At some time, I used to be properly mindful that it could go Improper and that I could turn out to be much less thriving, but I just overlooked that. Curiosity has constantly been my strongest driving pressure. And by chance it all labored out.’

A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola

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Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic buildings to sample spatial boundaries for microorganisms and biomimetic vesicles with reconstituted protein networks and this assess the fundamental function of spatial confinement in the molecular and cellular amount. Our jobs involve the subsequent:

Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation

What if, in place of making use of conventional prime-down silicon electronics, transistors might be crafted from the bottom up using solitary natural molecules as the switching things? This idea, which turned the basis of currently’s area of molecular electronics, cees dekker initially emerged inside the nineteen seventies.

Resolving the phase dimensions in condensin-pushed DNA loop extrusion identifies ATP binding since the phase-creating approach

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division

2006, initial demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in stable-point out nanopores; and initial estimate of electrokinetic Strength conversion inside of a nanofluidic channel

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes

 At last, I'll briefly sketch some of our Suggestions to investigate the constructing of artificial cells, exclusively our initially ways to determine artificial mobile division.